Biggest Mistake on a Resume is...

not proofreading or getting somebody else to proofread your resume. Many, many times a resume will be thrown directly into the trash if there is even one tiny typo.

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Here are some links that can help:

20 Most Common Grammatical Errors - this is a great refresher in basic grammar.

Common Words That Sound Alike - the its/it's, there/they're/their etc. site; some of the MOST COMMON problems I see.

Punctuation - The University of Ottawa also has this site on correct punctuation usage.

What other mistakes will get your resume into the recycle bin?